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10 items found

Project 01 January 1970

A costimulatory power-boost for HIV-specific T-cells through GITR activation

People infected with HIV have nowadays almost the average life expectancy of the...
Project 01 January 1970

Activation of latent HIV virus

HIV therapy keeps the virus under control, but does not provide a cure. One caus...
Project 01 January 1970

Development of a natural drug 'mimic' derived from dendritic cells that activate latent HIV-1 and potentially could cure infected patients

HIV-1 can infect cells from the immune system without producing new viruses. The...
Project 01 January 1970

HIV envelope trimer vaccines that engage desirable germline antibodies

Despite 30 years of intensive research, an effective HIV-1 vaccine remains elusi...
Project 01 January 1970

Investigation of the central nervous system as a potential HIV reservoir during combination antiretroviral therapy.

The major obstacle to HIV cure is presence of a stable reservoir of latently inf...
Project 01 January 1970

Langerhans cell antiviral mechanisms control HIV

AMC researcher, Theo Geijtenbeek, previously discovered that certain immune cell...
Project 01 January 1970

Research on HIV latency in the viral reservoir

Dr. Monique Nijhuis aims to characterize the latently HIV-infected viral reservo...
Project 01 January 1970

Role of dendritic cells in HIV response

Dentritic cells play an important role in the immune system. As soon as a pathog...
Project 01 January 1970

Targeting BAF complex to reverse HIV latency

There is no drug that can cure HIV. The HIV virus can become latent and therefor...
Project 01 January 1970

The FIND study: core-needle biopsies to detect the hidden HIV reservoirs in hard-to-reach tissue compartments of well-controlled and uncontrolled HIV-patients

The major obstacle to an HIV cure is the presence of a persistent viral reservoi...

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